News Animals Pesticides Mess with Immunity: Double whammy promotes frog deformities By John Pickrell July 10, 2002 at 2:00 pm - More than 2 years ago Share this:Share Share via email (Opens in new window) Email Click to share on Facebook (Opens in new window) Facebook Click to share on Reddit (Opens in new window) Reddit Click to share on X (Opens in new window) X Click to print (Opens in new window) Print Agricultural pollutants may conspire with parasites to derail frog development in many regions of North America, according to a new study. FREAKY FROG. Amphibians infected with parasites sport extra legs. Kiesecker/Penn State University Malformed frogs–with bent spines and extra or missing hind limbs–have been documented since the 1700s.