Old-fashioned gene hunting wasn’t terribly efficient.
Geneticists typically pursued one gene at a time, armed only with guesses—usually
wrong—about
which chunks of genetic code might be linked to human disease.
Geneticists managed to bag a few trophies anyway—genes
for Huntington’s chorea and cystic fibrosis, for example—mostly
in rare diseases caused by a problem in a single, high-powered gene.
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