News Health & Medicine Marker signals esophageal cancer By Nathan Seppa November 8, 2004 at 7:11 pm - More than 2 years ago Share this:Share Share via email (Opens in new window) Email Click to share on Facebook (Opens in new window) Facebook Click to share on Reddit (Opens in new window) Reddit Click to share on X (Opens in new window) X Click to print (Opens in new window) Print A genetic abnormality in people with cancer of the esophagus might guide physicians in diagnosing and treating such patients and could become an indicator of cancer recurrences, report researchers at the University of Maryland School of Medicine in Baltimore. The scientists found that in tumor tissue from 48 of 52 people with adenocarcinoma of the esophagus, a gene that encodes a tumor-suppressing protein called APC had been shut down.