Irreproducible life sciences research in U.S. costs $28 billion

Problems with preclinical studies often stem from flaws in experimental design and materials

flaws in research

BIG SPENDERS  Preclinical research is all too often irreproducible. Its flaws, which tend to stem from four broad categories, cost big bucks.

L.P. Freedman, I.M. Cockburn and T.S. Simcoe/PLOS Biology 2015, adapted by M. Telfer

Around half of all preclinical research in the United States is not reproducible (SN: 1/24/15, p.