Immune system follows circadian clock

Mice with jet lag have boosted supply of cells linked to inflammation

UPSET CLOCK  Disrupting a mouse’s internal clock boosts the abundance of one type of immune cell, TH17 (false-colored green), in the lining of the intestines (gray fingerlike projections). The extra immune cells may make animals prone to inflammatory diseases.

Courtesy of Xiaofei Yu, Shipra Vaishnava and Yuhao Wang

Jet lag goofs up more than just sleep schedules: Tinkering with the body’s clock confuses the immune system too.