Discovery of how to prod a patient’s immune system to fight cancer wins a Nobel

Two scientists share the prize for identifying proteins that act as brakes on tumor-fighting T cells

James Allison and Tasuku Honjo

THERAPY WIN The discovery of two immune system regulators and their role in cancer has led to a new way to provide therapy for patients — and has garnered the Nobel Prize in physiology or medicine for James Allison (left) and Tasuku Honjo (right).

From left: University of Texas MD Anderson Cancer Center; Kyoto University Institute for Advanced Study

Stopping cancer by removing brakes on the immune system has earned James P.