How obesity makes it harder to taste

Inflammation linked to the disease caused the loss of taste buds in mice

progenitor cells

BYE BYE BUDS  Mice that became obese on a high-fat diet (right) lost a quarter of their taste buds (stained red) and also had fewer progenitor cells (stained green) — which give rise to new taste buds — than mice of a healthy weight on a regular diet (left).

A. Kaufman et al/PLOS Biology 2018

As mice plumped up on a high-fat diet, some of their taste buds vanished.