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Ebola gatekeeper protein identified

Mice lacking cellular transport molecule protected against infection

illustration of Ebola entering the cell

VIRAL ENTRY  The Ebola virus hijacks a protein called NPC1 to invade a host cell.

Albert Einstein College of Medicine

By Meghan Rosen

- More than 2 years ago

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Ebola relies on a molecular “inside man” to sneak into cells.

Mice lacking the virus’s accomplice, a protein called NPC1, are completely protected from Ebola infection, scientists report May 26 in mBio.