News Genetics

Gene editing of human embryos gets rid of a mutation that causes heart failure

Success in correcting DNA defect inches use of CRISPR closer to clinical trial

fertilized human eggs and embryos

IN GOOD REPAIR  CRISPR/Cas9 has corrected a gene defect in fertilized human eggs (left) without hampering embryo development. Four-cell embryos (middle) and blastocyst-stage embryos — about five days old — (right) carrying the CRISPR/Cas9 gene editor appear normal.

OHSU

By Tina Hesman Saey

- More than 2 years ago

For the first time in the United States, researchers have used gene editing to repair a mutation in human embryos.