Brain holds more than one road to fear

Drug elicits anxiety-producing reactions in people without working amygdalae

MRI scans

FEAR FACTORS  Despite extensive damage in their amygdalae (red circles in these MRI scans), twin sisters A.M. and B.G. still can experience anxiety prompted by bodily cues, a new study shows.  

S. Khalsa et al/Journal of Neuroscience 2016

In a pair of twin sisters, a rare disease had damaged the brain’s structures believed necessary to feel fear.