Body and Brain: Possible link between inflammation and bipolar disorder

Bipolar disorder scrawls a molecular John Hancock across the brains of some people. The signature is sometimes visible even before symptoms start, researchers in the Netherlands report.

A team led by Hemmo Drexhage, a clinical immunologist at Erasmus Medical Center in Rotterdam, found that certain white blood cells, called monocytes, pump up activity of various genes in people who have bipolar disorder.