Big data reveals hints of how, when and where mental disorders start

New genetic complexities emerge for schizophrenia, bipolar disorder and autism

Lab-grown brain organoids

ON THE BRAIN  Lab-grown brain organoids (one shown) mimic the real thing, analyses suggest. Along with other parts of a large research effort called PsychENCODE, the organoid results may offer new clues about psychiatric diseases such as schizophrenia.

Vaccarino Lab

Psychiatric disorders’ many complexities have stymied scientists looking for clear genetic culprits.