Back to Genetics: DNA variant may code for lumbar pain

It’s now tempting to blame your aching back on Mom and Dad. Researchers have discovered an inheritable gene variation that may increase susceptibility to lumbar-disk disease, a common precursor of lower-back pain.

The finding may lead to ways to identify patients at risk for lumbar-disk disease and to new drugs for treating it, says the study’s lead investigator, Shiro Ikegawa of the Institute of Physical and Chemical Research in Tokyo.