Anticancer Protein Locks onto DNA
- More than 2 years ago
Scientists now have a toehold on a slippery problem in cancer biology: the action of BRCA1, the gene most likely to be mutated in inherited breast cancer.
In its normal form, the gene encodes a tumor-suppressing protein, BRCA1. Previous genetic studies suggested that this protein protects against cancer by aiding in the repair of damaged DNA (SN: 4/15/00, p.