Adaptive no more

A potential benefit in prehistoric lean times, genetic variant may increase risk of gestational diabetes today

A genetic variation that may increase a woman’s risk of gestational diabetes is widespread today because it was actually beneficial to early agricultural populations, a new study suggests.

Pregnant women who carry two copies of a low-activity form of the gene GIP have higher blood-glucose levels — a marker of gestational diabetes risk — Sheau Yu Teddy Hsu of Stanford University and colleagues report online February 7 in Diabetes.