In mice, a high-fat diet cuts a ‘brake’ used to control appetite

The result shows how food can change the brain’s drive to eat

a very obese mouse

CHOW  After weeks on a high-fat diet, certain cells showed less activity in part of the appetite-controlling part of the brain in mice, results that suggest the fatty diet encourages overeating.

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A gut-busting diet may set the brain up for more of the same.