Psychotic Biology: Genes yield clues to schizophrenia’s roots

Scientists have identified two genes that, in certain molecular guises, may contribute to schizophrenia by disrupting transmission of a crucial chemical messenger in the brain.

While the presence of each gene variant by itself makes it more likely that a person will develop this severe mental disorder, this risk is greatly magnified when the two occur together, according to a team led by geneticist Daniel Cohen of the biotechnology firm Genset S.A.