Protein may be target for Crohn’s therapy

A protein called MIF–short for macrophage migration inhibitory factor–plays a central role in the process of inflammation. Researchers now report that MIF’s actions extend to the intestines. Their findings suggest that the protein perpetuates the chronic inflammation that characterizes Crohn’s disease, a painful gut disorder.

A view of macrophage migration inhibitory factor, a protein now implicated in Crohn’s disease.