Law and Disorder: Chance fluctuations can rule the nanorealm

Whether it’s the gasoline-to-motion transformation of automobiles or the electricity-to-cooling action of refrigerators, all processes squander energy. They vent that waste in the form of heat. It’s a law of thermodynamics, and no one has ever witnessed a sustained violation of it.

On the minute scales of cells and molecules, however, brief reversals of the usual rules routinely occur.