Anti-inflammatory drug may unleash TB

Physicians prescribing a drug that counteracts arthritis and other inflammatory diseases may in rare cases awaken dormant tuberculosis, researchers report in the Oct. 11 New England Journal of Medicine.

The drug, called infliximab and known by the trade name Remicade, suppresses a protein called tumor necrosis factor-alpha, or TNF-alpha, an immune system protein that causes swelling.